Back to results
US 7,022,821 B1Granted
Antibody kit for the detection of TADG-15 protein
OwnerTimothy J. O'Brien, Hirotoshi Tanimotoinventors
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
OwnerTimothy J. O'Brien, Hirotoshi Tanimotoinventors
Estimating the term…
The present invention provides DNA encoding a TADG-15 protein as well as a TADG-15 protein. Also provided is a vector capable of expressing the DNA of the present invention adapted for expression in a recombinant cell and regulatory elements necessary for expression of the DNA in the cell. The present invention further provides for methods of inhibiting TADG-15 expression and/or protease activity, methods of detecting TADG-15 mRNA and/or protein and methods of screening for TADG-15 inhibitors. Additionally, the present invention provides for cell-specific targeting via TADG-15 and methods of vaccinating an individual against TADG-15. The instant invention also includes a kit containing antibodies for the detection of TADG-15 protein. The methods described are useful in the diagnosis, treatment and prevention of cancer, particularly breast and ovarian cancer.
A kit for detecting a Tumor Antigen Derived Gene-15 (TADG-15) protein, which is SEQ ID No. 2, comprising:
An antibody specific for a Tumor Antigen Derived Gene-15 (TADG-15) protein, which is SEQ ID No. 2, wherein said TADG-15 protein has a molecular size of 100 kDa and comprises CUB, LDLR and serine protease domains.
A kit for detecting a Tumor Antigen Derived Gene-15 (TADG-15) protein, which is SEQ ID No. 2, comprising:
An antibody specific for a Tumor Antigen Derived Gene-15 (TADG-15) protein, which is SEQ ID No. 2, wherein said TADG-15 protein has a molecular size of 100 kDa.
A kit for detecting a Tumor Antigen Derived Gene-15 (TADG-15) protein, which is SEQ ID No. 2, comprising:
An antibody specific for a Tumor Antigen Derived Gene-15 (TADG-15) protein, which is SEQ ID No. 2, wherein said TADG-15 protein comprises CUB, LDLR and serine protease domains.
Dependencies are inferred from the claim text.