Isolated nucleic acid molecule coding for tumor rejection antigen precursors MAGE-C1 and MAGE-C2 and uses thereof
AssigneeLudwig Institute for Cancer Research
InventorsSophie Lucas, Charles De Smet, Thierry Boon-Falleur
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Abstract
The invention relates to isolated nucleic acid molecules which code for antigens expressed by tumor cells which maybe recognized by cytotoxic T cells, leading to lysis of the tumor cells which express it. This invention also relates to vectors which are designed to encode the antigen expressed by tumor cells and also to cells transfected by the nucleic acid molecules or vectors which comprise the nucleic acid molecules. Various therapeutic and diagnostic uses arising out of the properties of the nucleic acid molecules and the antigens for which these code are also part of this invention.
Claims2
An isolated tumor rejection antigen precursor (TRAP) comprising the amino acid sequence encoded by a nucleic acid molecule comprising the nucleotide sequence as set forth in SEQ ID NO:
- 18.
Dependencies are inferred from the claim text.