Lubricious ophthalmic solutions
OwnerLeonard Macklesinventor
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Abstract
There are provided lubricious ophthalmic solutions having a pH of between about 7.0 and about 8.0, consisting essentially of an aqueous solution of from about 0.5–4% by weight of a monographed polyol, borate calculated as the borate equivalent of 20–100% by weight of boric acid relative to said polyol, from about 0.1 to about 1.00% by weight of monographed polysorbate, a monographed preservative and a buffer. Suitably the polyol is polyvinyl alcohol In addition to polyvinyl alcohol (hereinafter PVA) the solution may include other monographed polymers as well as monographed pharmacologically active substances.
Claims21
A lubricious ophthalmic solution having a pH of between about 7.0 and about 8.0, consisting essentially of:
- from about 0.5–4% by weight of a monographed polyol,
- borate calculated as the borate equivalent of 20–100% by weight of boric acid relative to said polyol,
- from about 0.1 to about 1.00% by weight of monographed polysorbate,
- the monograph permitted amount 0.1 wt of monographed preservative a buffer and water to 100% wt.
Dependencies are inferred from the claim text.