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US 7,022,733 B2Granted
Substituted 2-phenyl benzofurans as estrogenic agents
AssigneeWyeth
InventorsChristopher P. Miller, Michael D. Collini, David H. Kaufman, Robert L. Morris, Robert R. Singhaus, Jr., John W. Ullrich, Heather A. Harris, James C. Keith, Jr., Leo M. Albert, Rayomand J. Unwalla
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Abstract
This invention provides estrogen receptor modulators of formula I, having the structure wherein R, R′, A, A′, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
Claims1
A method of treating or inhibiting endometriosis in a mammal in need thereof, which comprises providing to said mammal an effective amount of a compound of formula I, having the structure
- wherein
- P and P′ are each, independently, hydrogen, alkyl of 1–6 carbon atoms, or acyl of 2–7 carbon toms;
- X is hydrogen or halogen;
- R is hydrogen, alkyl of 1–6 carbon atoms, halogen, —CN, or —CHO;
- R′ is alkoxy of 1–6 carbon atoms, or cyanoalkyl having 1–6 carbon atoms in the alkyl moiety;
- or a pharmaceutically acceptable salt thereof.
3 more elements
Dependencies are inferred from the claim text.