Farnesyl transferase inhibitors

A compound consisting of a first compound and a second compound wherein each of said first compound and each of said second compound is independently selected from the group consisting of a compound of formula (I):

• wherein:
• R1 is H, lower alkyl, cycloalkylthio, or lower alkylthio, or, together with R2, form —CH2— or —C(CH3)2—;
• each of R2 and R3, independently, is H or lower alkyl;
• R4 is H2 or O;
• R5 is H, or substituted or unsubstituted lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl, cycloalkyl lower alkyl, cycloalkenyl, cycloalkenyl lower alkyl, aryl, aryl lower alkyl, heterocyclyl, or heterocyclyl lower alkyl, wherein the substituent is lower alkyl, —O—R10, —S(O)mR10 (where m is 0, 1, or 2), —N(R10)(R11), —N—C(O)—R10, —NH—(SO2)—R10, —CO2—R10, —C(O)—N(R10)(R11), or —(SO2)—N(R10)(R11);
• each of R6 and R7, independently, is H, —C(O)NHCHR13CO2R14, or substituted or unsubstituted lower alkyl, cycloalkyl, cycloalkyl lower alkyl, cyloalkenyl, cycloalkenyl lower alkyl, aryl, aryl lower alkyl, heterocyclyl, or heterocyclyl lower alkyl, wherein the substituent is OH, lower alkyl, lower alkoxy, aryloxy, aryl lower alkoxy, —N(R10)(R11), —COOH, —C(O)—N(R10)(R11), or halo;
• each of R8 and R9, independently, is H, or substituted or unsubstituted lower alkyl, cycloalkyl, cycloalkyl lower alkyl, cyloalkenyl, cycloalkenyl lower alkyl, aryl, aryl lower alkyl, heterocyclyl, or heterocyclyl lower alkyl, wherein the substituent is OH, lower alkyl, lower alkoxy, —N(R10)(R11), —COOH, —C(O)—N(R10)(R11), or halo;
• and
• each of R10 and R11, independently, is H, lower alkyl, aryl, aryl lower alkyl, cycloalkyl, cycloalkyl lower alkyl, heterocyclyl, or heterocyclyl lower alkyl;
• R12 is NR9, S, or O;
• R13 is substituted or unsubstituted lower alkyl wherein the substituent is lower alkyl, —OR10, S(O)mR10 (wherein m is 0, 1, or 2) or —N(R10)(R11);
• and
• R14 is H or lower alkyl;
• wherein R1 in said first compound and R1 in said second compound in combination, form a disulfide bond;
• or a pharmaceutically acceptable salt thereof.