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US 7,022,697 B2Granted
4-(Oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]-nonane derivatives, preparation and therapeutic use thereof
AssigneeSanofi-Aventis
InventorsFrédéric Galli, Odile Leclerc, Alistair Lochead
Life of this patent
Estimating the term…
Abstract
The invention relates to compounds of the Formula I, to pharmaceutical compositions comprising them, and to the method of use thereof in the treatment or prevention of disorders linked to a dysfunction of the nicotinic receptors.
Claims6
A compound of the formula (I)
- in which R represents a (C3–C6)cycloalkyl group or a phenyl group which is optionally substituted by one or more groups selected from a halogen atom, a (C1–C6) alkyl, (C1–C6)alkoxy, nitro, amino, di(C1–C3)alkylamino, trifluoromethoxy, trifluoromethyl, cyano, hydroxyl or methylenedioxy group, or a piperid-1-yl or 4-morpholinyl or pyrrolidin-1-yl or azetidin-1-yl or azepin-1-yl or pyridyl or piperazinyl or thienyl or pyrazinyl or furyl or benzofuryl or benzothienyl or indolyl or pyrimidinyl or isoxazolyl or phenoxazinyl or dibenzofuryl or dibenzothienyl or pyrrolyl or naphthyl group, each of which groups may optionally be substituted by one or more groups selected from a halogen atom or a (C1–C6)alkyl, (C1–C6)alkoxy, trifluoromethoxy, trifluoromethyl, nitro, cyano, hydroxyl, amino, (C1–C3)dialkylamino or (C3–C8)cycloalkylamino group, in the form of a base or an addition salt with an acid.
Dependencies are inferred from the claim text.