Combination of loteprednol and antihistamines
AssigneeAsta Medica Aktiengesellschaft
InventorsIstvan Szelenyl, Degenhard Marx, Sabine Heer, Juergen Engel
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Abstract
The present invention relates to a novel combination of a soft steroid, in particular loteprednol, and at least one antihistamine, such as, for example, azelastine and/or levocabastine, for simultaneous, sequential or separate administration in the local treatment of allergies and airway disorders, for example of allergic rhinitis (rhinoconjunctivitis).
Claims12
A pharmaceutical composition comprising an effective amount of loteprednol or a pharmaceutically acceptable ester thereof and an effective amount of azelastine.
A method for the treatment of one or more allergic disorders selected from the group consisting of allergic rhinitis and allergic conjunctivitis comprising administering to a person in need thereof, an effective amount of loteprednol or a pharmaceutically acceptable ester thereof and an effective amount of intranasally or intraocularly administrable azelastine optionally together with customary excipients or vehicles, for simultaneous, sequential or separate administration.
A method for the treatment and prophylaxis of one or more allergic disorders selected from the group consisting of allergic rhinitis and allergic conjunctivitis, comprising administering to a person in need thereof, an effective amount of loteprednol and an effective amount of azelastine, wherein the loteprednol or a pharmaceutically acceptable ester thereof and the azelastine is administered simultaneously, sequentially or separately, optionally together with customary excipients or vehicles.
A method for the treatment of one or more allergic disorders selected from the group consisting of allergic rhinitis and allergic conjunctivitis comprising administering to a patient in need thereof, a combination of an effective amount of loteprednol or a pharmaceutically acceptable ester thereof and an effective amount of azelastine for simultaneous, sequential or separate administration.
Dependencies are inferred from the claim text.