Compositions and methods for cleaning contact lenses
AssigneeNovartis AG
InventorFu-Pao Tsao
Life of this patent
Estimating the term…
Abstract
A composition for disinfecting a contact lens comprising an effective disinfecting amount of hydrogen peroxide and a surfactant comprising a copolymer of hydrophobe and hydrophile blocks the structure: HO-(hydrophobe)x-(hydrophile)y-(hydrophobe)x-H or HO-(hydrophile)y-(hydrophobe)x-(hydrophile)y-H where x and y are integers reflecting the respective hydrophile and hydrophobe blocks of said copolymer; and the hydrophile component of the block copolymer constitutes less than 50 weight percent of the block copolymer. The block copolymer has a Ross-Miles foam height (ASTM designation D-1173-53; 0.1%, at 50° C.) of less than 1 mm.
Claims38
A composition for disinfecting a contact lens,
- comprising
- an effective disinfecting amount of hydrogen peroxide and a surfactant comprising a block copolymer of hydrophobe and hydrophile blocks of the structure:
- HO-(hydrophobe)x-(hydrophile)y-(hydrophobe)x-H
- wherein x and y are integers reflecting the respective hydrophile and hydrophobe blocks of said copolymer, and the hydrophile component of the block copolymer constitutes less than 50 weight percent of the block;
- and
- being characterized by being incapable of foaming at any time within a disinfection cycle carried out in a disinfection cup having a platinum-coated plastic disk that catalytically decomposes hydrogen peroxide generating oxygen gas bubbles, so significantly to cause overflow of the composition from the disinfection cup.
A composition for disinfecting a contact lens comprising an aqueous solution of an effective disinfecting amount of hydrogen peroxide and a polyoxyethylene/polyoxypropylene block copolymer having the structure:
- wherein x and y are integers reflecting the respective polyethylene oxide and polypropylene oxide blocks of said copolymer;
- and the polyoxyethylene component of the block copolymer constitutes less than 50 weight percent of the block copolymer;
- wherein said block copolymer has a Ross-Miles foam height (ASTM designation D-1173-53;
- 0.1%, at 50° C.) of less than 1 mm.
A composition for disinfecting a contact lens as claimed in claim 21, wherein said surfactant is less than 0.1% by weight of the solution.
A composition for disinfecting a contact lens comprising an aqueous solution of:
- an effective disinfecting amount of hydrogen peroxide;
- a buffer compatible with ocular tissue;
- a hydrogen peroxide stabilizer comprising a diphosphonic acid alkanol;
- a tonicity component;
- and
- polyoxyethylene/polyoxypropylene block copolymer having the structure:
- wherein x and y are integers reflecting the respective polyethylene oxide and polypropylene oxide blocks of said copolymer,
- wherein said block copolymer has a Ross-Miles foam height (ASTM designation D-1173-53;
- 0.1%, at 50° C.) of less than 1 mm.
A method of disinfecting a contact lens comprising the steps of:
- (a) contacting a contact lens with an aqueous solution of an effective disinfecting amount of hydrogen peroxide and a polyoxyethylene/polyoxypropylene block copolymer having the structure:
- wherein x and y are integers reflecting the respective polyethylene oxide and polypropylene oxide blocks of said copolymer;
- and the polyoxyethylene component of the block copolymer constitutes less than 50 weight percent of the block copolymer;
- wherein said block copolymer has a Ross-Miles foam height (ASTM designation D-1173-53;
- 0.1%, at 50° C.) of less than 1 mm;
- and
- (b) neutralizing said hydrogen peroxide by catalytic decomposition.
Dependencies are inferred from the claim text.