4-trifluoromethylpyrazolyl-substituted pyridines and pyrimidines

A compound of the formula (I) or an N-oxide or salt thereof,

• in which the radicals and indices have the following definitions:
• Z is N
• A is
• R1 and R2 independently are each hydrogen, halogen, cyano, isocyano, OH, COOR10, COR10, CH2OH, CH2SH, CH2NH2, NO2, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C3–C6)-cycloalkyl, (C1–C4)-alkoxy, halogen-(C1–C4)-alkoxy, (C1–C2)-alkoxy-(C1–C2)-alkyl, (C2–C4)-alkenyl, (C2–C4)-alkynyl, (C3–C4)-alkenyloxy, (C3–C4)-alkynyloxy, (C1–C2)-alkylthio-(C1–C2)-alkyl, S(O)nR9, (C1–C2)-alkylsulfonyl-(C1–C2)-alkyl, NH2, (C1–C4)-alkyl-NH, (C1–C3)-alkyl-CO—NH, (C1–C4)-alkyl-SO2NH or di-(C1–C4)-alkylamino;
• R3 and R4 independently are each hydrogen, halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy or halo-(C1–C4)-alkoxy;
• R5 is halogen, cyano, (C1–C4)-alkyl, halo-(C2)-alkyl, halo-(C3)-alkyl, halo-(C4)-alkyl, (C1–C4)-alkoxy, halo-(C1–C4)-alkoxy, halo-(C1–C4)-alkylthio, (C3–C5)-cycloalkyl, halo-(C3–C5)-cycloalkyl, SF5, S(O)nR9, (C2–C4)-alkenyl or (C2–C4)-alkynyl;
• R6 is hydrogen, halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy, halo-(C1–C4)-alkoxy or S(O)nR9;
• R9 is hydrogen, (C1–C4)-alkyl or halo-(C1–C4)-alkyl;
• R10 is hydrogen or (C1–C4)-alkyl;
• and
• n is 0, 1 or 2.

A compound of the formula (I) or an N-oxide or salt thereof,

• in which the radicals and indices have the following definitions:
• Z is N
• A is
• R1 and R2 independently are each hydrogen, halogen, cyano, isocyano, OH, COOR10, COR10, CH2OH, CH2SH, CH2NH2, NO2, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C3–C6)-cycloalkyl, (C1–C4)-alkoxy, halogen-(C1–C4)-alkoxy, (C1–C2)-alkoxy-(C1–C2)-alkyl, (C2–C4)-alkenyl, (C2–C4)-alkynyl, (C3–C4)-alkenyloxy, (C3–C4)-alkynyloxy, (C1–C2)-alkylthio-(C1–C2)-alkyl, S(O)nR9, (C1–C2)-alkylsulfonyl-(C1–C2)-alkyl, NH2, (C1–C4)-alkyl-NH, (C1–C3)-alkyl-CO—NH, (C1–C4)-alkyl-SO2NH or di-(C1–C4)-alkylamino;
• R3 is hydrogen, halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy or halo-(C1–C4)-alkoxy;
• R4 is halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy or halo-(C1–C4)-alkoxy;
• R5 is halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy, halo-(C1–C4)-alkoxy, halo-(C1–C4)-alkylthio, (C3–C5)-cycloalkyl, halo-(C3–C5)-cycloalkyl, SF5, S(O)nR9, (C2–C4)-alkenyl or (C2–C4)-alkynyl;
• R6 is hydrogen, halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy, halo-(C1–C4)-alkoxy or S(O)nR9;
• R9 is hydrogen, (C1–C4)-alkyl or halo-(C1–C4)-alkyl;
• R10 is hydrogen or (C1–C4)-alkyl;
• and
• n is 0, 1 or 2.

A compound of the formula (I) or an N-oxide or salt thereof,

• in which the radicals and indices have the following definitions:
• Z is N
• A is
• R1 and R2 independently are each hydrogen, halogen, cyano, isocyano, OH, COOR10, COR10, CH2OH, CH2SH, CH2NH2, NO2, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C3–C6)-cycloalkyl, (C1–C4)-alkoxy, halogen-(C1–C4)-alkoxy, (C1–C2)-alkoxy-(C1–C2)-alkyl, (C2–C4)-alkenyl, (C2–C4)-alkynyl, (C3–C4)-alkenyloxy, (C3–C4)-alkynyloxy, (C1–C2)-alkylthio-(C1–C2)-alkyl, S(O)nR9, (C1–C2)-alkylsulfonyl-(C1–C2)-alkyl, NH2, (C1–C4)-alkyl-NH, (C1–C3)-alkyl-CO—NH, (C1–C4)-alkyl-SO2NH or di-(C1–C4)-alkylamino;
• R3 is halogen, cyano, (C2)-alkyl, (C3)-alkyl, (C4)-alkyl, halo-(C1–C4)-alkyl, C1–C4)-alkoxy or halo-(C1–C4)-alkoxy;
• R4 is hydrogen, halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy or halo-(C1–C4)-alkoxy;
• R5 is halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy, halo-(C1–C4)-alkoxy, halo-(C1–C4)-alkylthio, (C3–C5)-cycloalkyl, halo-(C3–C5)-cycloalkyl, SF5, S(O)nR9, (C2–C4)-alkenyl or (C2–C4)-alkynyl;
• R6 is hydrogen, halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy, halo-(C1–C4)-alkoxy or S(O)nR9;
• R9 is hydrogen, (C1–C4)-alkyl or halo-(C1–C4)-alkyl;
• R10 is hydrogen or (C1–C4)-alkyl;
• and
• n is 0, 1 or 2.

A compound of the formula (I) or an N-oxide or salt thereof,

• in which the radicals and indices have the following definitions:
• Z is N
• A is
• R1 is isocyano, OH, COOH, CO2CH3, CO2(C3-alkyl), CO2(C4-alkyl), COH, COCH3, CO(C2-alkyl), CO(C3-alkyl), CO(C4-alkyl), CH2OH, CH2SH, CH2NH2, NO2, (C2)-alkyl, (C3 )-alkyl, (C4)-alkyl, halo-(C2)-alkyl, halo-(C3)-alkyl, halo-(C4)-alkyl, (C3–C6)-cycloalkyl, (C2)-alkoxy, (C3)-alkoxy, (C4)-alkoxy, halogen-(C1–C4)-alkoxy, (C2)-alkoxy-(C1–C2)-alkyl, (C1)-alkoxy-(C2)-alkyl, (C2–C4)-alkenyl, (C2–C4)-alkynyl, (C3–C4)-alkenyloxy, (C3–C4)-alkynyloxy, (C1–C2)-alkylthio-(C1–C2)-alkyl, S(O)nR9, (C1–C2)-alkyl sulfonyl-(C1–C2)-alkyl, NH2, (C1–C4)-alkyl-NH, (C1–C3)-alkyl-CO—NH, (C1–C4)-alkyl-SO2NH or di-(C1–C4)-alkylamino;
• R2 is Br, F, cyano, isocyano, OH, COOR10, COR10, CH2OH, CH2SH, CH2NH2, NO2,(C3)-alkyl, (C4)-alkyl, halo-(C2)-alkyl, halo-(C3)-alkyl, halo-(C4)-alkyl, (C3–C6)-cycloalkyl, (C2)-alkoxy, (C3)-alkoxy, (C4)-alkoxy, halogen-(C1–C4)-alkoxy, (C1–C2)-alkoxy-(C1–C2)-alkyl, (C2–C4)-alkenyl, (C2–C4)-alkynyl, (C3–C4)-alkenyloxy, (C3–C4)-alkynyloxy, (C1–C2)-alkylthio-(C1–C2)-alkyl, S(O)nR9, (C1–C2)-alkylsulfonyl-(C1–C2)-alkyl, NH2, (C1–C4)-alkyl-NH, (C1–C3)-alkyl-CO—NH, (C1–C4)-alkyl-SO2NH or di-(C1–C4)-alkylamino;
• R3 and R4 independently are each hydrogen, halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy or halo-(C1–C4)-alkoxy;
• R5 is halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy, halo-(C1–C4)-alkoxy, halo-(C1–C4)-alkylthio, (C3–C5)-cycloalkyl, halo-(C3–C5)-cycloalkyl, SF5, S(O)nR9, (C2–C4)-alkenyl or (C2–C4)-alkynyl;
• R6 is hydrogen, halogen, cyano, (C1–C4)-alkyl, halo-(C1–C4)-alkyl, (C1–C4)-alkoxy, halo-(C1–C4)-alkoxy or S(O)nR9;
• R9 is hydrogen, (C1–C4)-alkyl or halo-(C1–C4)-alkyl;
• R10 is hydrogen or (C1–C4)-alkyl;
• and
• n is 1 or 2.