US 7,022,521 B2 · Methods and compositions for treating platelet-related disorders using MPL pathway inhibitory agents

Abstract

The invention relates to the treatment of subjects for the purpose inhibiting vaso-occlusive events, including thrombosis and embolism, by administering agents which reduce the number of circulating platelets to low or below normal levels. Methods and pharmaceutical preparations comprising such agents are provided.

Claims20

Dependent claims

A method for treating a subject having above normal platelet count comprising

administering to the subject in need of such treatment an MPL pathway inhibitory agent in an amount effective to reduce platelet count to at least a low normal level.

Dependencies are inferred from the claim text.

Facts

Application

10/602,293Filed 24 Jun 2003 · continuation

Priority

21 Sep 1999

Published

US 2004/0087035 A16 May 2004

Granted

4 Apr 2006

Term ends

Not estimatedThe source records don’t support an estimate.

Classification24 codes

A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…
A61K 9/1647
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers: polyesters, e.g. poly
A61K 9/204
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers:…
A61K 31/00
Medicinal preparations containing organic active ingredients

Family

Application60/154,929Us provisional application · filed 21 Sep 1999

Application09/666,224Parent of this division · filed 21 Sep 2000

Application10/117,837Parent of this continuation · filed 8 Apr 2002

US 2004/0087035 A1Pre-grant publication · published 6 May 2004

US 6,376,242 B1Parent of this division

Application10/117,837Parent of this division

US 2002/0119144 A1Published application

US 7,022,521 B2This patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Facts

Application

10/602,293Filed 24 Jun 2003 · continuation

Priority

21 Sep 1999

Published

US 2004/0087035 A16 May 2004

Granted

4 Apr 2006

Term ends

Not estimatedThe source records don’t support an estimate.

Classification24 codes

A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…
A61K 9/1647
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers: polyesters, e.g. poly
A61K 9/204
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers:…
A61K 31/00
Medicinal preparations containing organic active ingredients

Family

Application60/154,929Us provisional application · filed 21 Sep 1999

Application09/666,224Parent of this division · filed 21 Sep 2000

Application10/117,837Parent of this continuation · filed 8 Apr 2002

US 2004/0087035 A1Pre-grant publication · published 6 May 2004

US 6,376,242 B1Parent of this division

Application10/117,837Parent of this division

US 2002/0119144 A1Published application

US 7,022,521 B2This patent

From the US filing history. Foreign family members aren’t listed.

Methods and compositions for treating platelet-related disorders using MPL pathway inhibitory agents

Life of this patent

Abstract

Claims20

Methods and compositions for treating platelet-related disorders using MPL pathway inhibitory agents

Life of this patent

Abstract

Claims20