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US 7,022,495 B2Granted
Method for sorting antifungal molecules acting on the glucanosyltransferase activity
AssigneeInstitut Pasteur
InventorsThierry Fontaine, Robbert Hartland, Isabelle Mouyna, Jean-Paul Latge
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Abstract
The invention discloses proteins having β(1-3)glucanosyltransferase type activities. These proteins can be used for detecting the antifungal activity of molecules.
Claims5
A process for detecting antifungal activity of a molecule comprising:
- combining a molecule to be tested with a protein having β-(1-3)-glycanosyltransferase type activity, wherein the protein comprises SEQ ID NO:3, and
- determining an effect of the molecule on the protein, wherein an effect on the β-(1-3)-glycanosyltransferase type activity by the molecule is indicative of a molecule having antifungal activity.
Dependencies are inferred from the claim text.