Fetally expressed gene as a human colon cancer marker
AssigneeChugai Seiyaku Kabushiki Kaisha
InventorsJun-Ichi Nezu, Asuka Ose
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Abstract
Novel fetal genes (fls353 and fls485) have been successfully isolated from human fetal liver-derived cDNAs. These genes were specifically expressed in tissues including fetal tissues which are thought to contain a large number of undifferentiated cells and actively differentiating/proliferating cells. High levels of expression of these genes were observed also in a variety of cancer cells. The proteins and genes encoding the proteins can be used as the tool for developing drugs for the treatment of tumors.
Claims21
An isolated nucleic acid encoding a protein comprising the amino acid sequence of SEQ ID NO:2.
An isolated nucleic acid encoding a polypeptide, the amino acid sequence of which consists of SEQ ID NO:2.
An isolated nucleic acid comprising the coding region of SEQ ID NO:1.
Dependencies are inferred from the claim text.