Back to results
US 7,022,125 B2Granted
Method and hemostatic patch for effecting local hemostasis
AssigneePerlei Medical Incorporated
InventorJörgen Boëthius
Life of this patent
Estimating the term…
Abstract
In a method for effecting hemostasis of a bleeding wound, an antifibrinolytic agent is applied to a substrate and the substrate with the antifibrinolytic agent applied thereto is placed onto the bleeding wound. A hemostatic patch has a substrate that is impregnated with the antifibrinolytic agent and is preferably enclosed in a foil package and is ready to use when the package is opened.
Claims40
A method for effecting hemostasis by affecting and maintaining the effects of coagulation of a bleeding wound, comprising the steps of:
- applying an antifibrinolytic agent to a complementary absorbent porous substrate selected from the group consisting of a medical compress, a patch, a sponge, a pad, a swab, and a dressing to create a hemostatic patch;
- detachably temporarily mounting the substrate against the wound, the substrate with the antifibrinolytic agent applied thereto being mounted onto the bleeding wound without adhering the substrate to the wound whereby the entire substrate is readily removable, the substrate being free of clot catalyzing reactive components and being free of hemostatic agents except for the antifibrinolytic agent, releasing the antifibrinolytic agent from the substrate into the wound, using the substrate to absorb blood and liquids from the bleeding wound, and simultaneously using the substrate to place the antifibrinolytic agent against the wound to affect and maintain the effects of coagulation as normally conducted by the body and to prevent clot dissolution.
A hemostatic patch to affect and maintain the effects of coagulation comprising:
- an absorbent porous clot promoting substrate selected from the group consisting of a medical compress, a patch, a sponge, a pad, a swab, and a dressing;
- and a complementary means for effecting hemostasis by affecting coagulation contained within the substrate, wherein the complementary means for effecting hemostasis by affecting coagulation is an antifibrinolytic agent, the substrate being free of clot catalyzing reactive components and being free of hemostatic agents except for the antifibrinolytic agent whereby the substrate comprises means for absorbing blood and liquids from a bleeding wound and for promoting clot formation without sealing any portion of the substrate to the wound by detachably temporarily mounting the substrate to the wound whereby the entire substrate is readily removable, the antifibrinolytic agent being releasably contained within the substrate whereby the antifibrinolytic agent is capable of being released into the wound, the antifibrinolytic agent comprising means for preventing clot dissolution, and the substrate and antifibrinolytic agent in combination being means to affect and maintain the effects of coagulation as normally conducted by the body.
A hemostatic medical kit comprising:
- one or more porous clot promoting substrates selected from the group consisting of a medical compress, a patch, a sponge, a pad, a swab, and a dressing for creating at least one hemostatic patch;
- and a complementary means for effecting hemostasis by enhancing coagulation, wherein the means for effecting hemostasis by enhancing coagulation is a solution of an antifibrinolytic agent for impregnating the one or more substrates, the antifibrinolytic agent being the sole hemostatic agent in the kit so that when the antifibrinolytic agent is applied to the substrate to form a hemostatic patch the substrate is free of clot catalyzing reactive components and is free of hemostatic agents except for the antifibrinolytic agent whereby the substrate comprises means for absorbing blood and liquids from a bleeding wound without sealing any portion of the substrate to the wound by detachably temporarily mounting the entire substrate to the wound whereby the substrate is readily removable, the antifibrinolytic agent being releasably containable within the substrate whereby the antifibrinolytic agent is capable of being released into the wound, the antifibrinolytic agent comprising means for preventing clot dissolution, and the substrate and antifibrinolytic agent in combination being means to affect and maintain the effects of coagulation as normally conducted by the body.
A hemostatic patch to affect and maintain the effects of coagulation comprising:
- an absorbent porous clot promoting substrate selected from the group comprising a medical compress, a patch, a sponge, a pad, a swab, and a dressing;
- and said substrate containing a coagulation enhancing substance for effecting the formation of a clot, said substance consisting of an antifibrinolytic agent, the substrate being free of clot catalyzing reactive components and being free of hemostatic agents except for the antifibrinolytic agent whereby said substrate comprises means to absorb blood and liquids from a bleeding wound without sealing any portion of the substrate to the wound by detachably temporarily mounting the substrate to the wound whereby the entire substrate is readily removable, the antifibrinolytic agent being releasably contained within the substrate whereby the antifibrinolytic agent is capable of being released into the wound, said antifibrinolytic agent functioning to prevent clot dissolution, and the substrate and antifibrinolytic agent in combination being means to affect and maintain the effects of coagulation as normally conducted by the body.
A method for affecting and maintaining the effects of coagulation of a bleeding wound, comprising the steps of:
- providing an absorbent porous clot promoting substrate selected from the group comprising a medical compress, a patch, a sponge, a pad, a swab, and a dressing;
- applying a coagulation enhancing substance to the substrate to create a hemostatic patch, wherein the coagulation enhancing substance consists of an antifibrinolytic agent and with the substrate being free of clot catalyzing reactive components and being free of hemostatic agents except for the antifibrinolytic agent;
- detachably temporarily mounting the substrate with the antifibrinolytic agent applied thereto onto a bleeding wound without adhering any portion of the substrate to the wound whereby the entire substrate is readily removable, releasing the antifibrinolytic agent from the substrate into the wound, using the substrate to absorb blood and liquids from the bleeding wound and simultaneously using the substrate to place the antifibrinolytic agent against the wound to prevent clot dissolution, and the substrate and antifibrinolytic agent affecting and maintaining the effects of coagulation as normally conducted by the body.
A method for effecting hemostasis by affecting and maintaining the effects of coagulation of a bleeding wound, comprising the steps of:
- applying tranexamic acid to a complementary absorbent porous substrate selected from the group consisting of a medical compress, a patch, a sponge, a pad, a swab, and a dressing to create a hemostatic patch;
- detachably temporarily mounting the substrate against the wound, the substrate with the tranexamic acid applied thereto being mounted onto the bleeding wound without adhering the substrate to the wound whereby the entire substrate is readily removable, the substrate being free of clot catalyzing reactive components and being free of hemostatic agents except for the tranexamic acid, releasing the tranexamic acid from the substrate into the wound, using the substrate to absorb blood and liquids from the bleeding wound, and simultaneously using the substrate to place the tranexamic acid against the wound to affect and maintain the effects of coagulation as normally conducted by the body and to prevent clot dissolution.
A hemostatic patch to affect and maintain the effects of coagulation comprising:
- an absorbent porous clot promoting substrate selected from the group consisting of a medical compress, a patch, a sponge, a pad, a swab, and a dressing;
- and a complementary means for effecting hemostasis by affecting coagulation contained within the substrate, wherein the complementary means for effecting hemostasis by affecting coagulation is tranexamic acid, the substrate being free of clot catalyzing reactive components and being free of hemostatic agents except for the tranexamic acid whereby the substrate comprises means for absorbing blood and liquids from a bleeding wound and for promoting clot formation without sealing any portion of the substrate to the wound by detachably temporarily mounting the substrate to the wound whereby the entire substrate is readily removable, the tranexamic acid being releasably contained within the substrate whereby the tranexamic acid is capable of being released into the wound, the tranexamic acid comprising means for preventing clot dissolution, and the substrate and tranexamic acid combination being means to affect and maintain the effects of coagulation as normally conducted by the body.
Dependencies are inferred from the claim text.