Endiandric acid H and its derivatives, process for their preparation and use thereof

A compound of the formula (I)

• wherein
• R1 and R2 together are —O—CH2—O—,
• R4 is
• CO2R3, CO2NHR3, CHO, CH2OR3, CH2OSi(R3)3, CH2Br, CH2CN, wherein R3 is,
• 1.0 H or
• 2.0 a C1–C6-alkyl, C2–C6-alkenyl, C2–C6-alkynyl or C6–C10-aryl group, in which alkyl, alkenyl and alkynyl are straight-chain or branched, and in which the alkyl, alkenyl and alkynyl groups are further mono- or disubstituted by:
• 2.1 —OH,
• 2.2 ═O,
• 2.3 —O—C1–C6-alkyl in which alkyl is straight-chain or branched,
• 2.4 —O—C2–C6-alkenyl in which alkenyl is straight-chain or branched,
• 2.5 —C6–C10-aryl,
• 2.6 —NH—C1–C6-alkyl in which alkyl is straight-chain or branched,
• 2.7 —NH—C2–C6-alkenyl in which alkenyl is straight-chain or branched,
• 2.8 —NH2 or
• 2.9 halogen,
• and in which the aryl groups are further mono- or disubstituted by substituents 2.1 or 2.3 to 2.9,
• in which the substituents 2.3, 2.4, 2.6 and 2.7 are further substituted by —CN, -amide or -oxime functions, and 2.5 are further substituted —CN or amide,
• or a stereoisomeric form of the compound of the formula (I) or a physiologically tolerated salt of the compound of the formula (I) or a salt of a stereoisomeric form of the compound of the formula (I) provided R4 is not CO2H.