Substituted benzothiazole amide derivatives

A compound of formula

• wherein
• R is lower alkoxy or halogen;
• R11 and R21, together with the N atom to which they are attached, form a heterocyclic ring, said heterocyclic ring being unsubstituted or substituted by lower alkyl, selected from the group consisting of
• 2-oxa-5-aza-bicyclo[2.2.1]heptane,
• 3-endo-hydroxy-8-aza-bicyclo[3.2.1]octane,
• 2-aza-bicyclo[2.2.2]octane,
• 1-oxo-2,8-diaza-spiro[4.5]decane,
• 3-aza-spiro[5.5]undecane,
• 8-aza-spiro[4.5]decane,
• 1-oxa-8-aza-spiro[4.5]decane,
• 1,8,8-trimethyl-3-aza-bicyclo[3.2.1]octane,
• [1,4]oxazepane,
• 2-oxa-5-aza-bicyclo[2.2.2]octane,
• 8-oxa-3-aza-bicyclo[3.2.1]octane,
• 1,4-diaza-bicyclo[3.2.1]octane,
• 2-aza-bicyclo[2.2.1]heptane and
• 3-aza-bicyclo[3.2.1]octane, or
• piperidin-1-yl, substituted by a substituent selected from the group —(CH2)n—NR′S(O)2-lower alkyl, —C(O)NR′2 and —(CH2)n-phenyl, said phenyl ring being unsubstituted or substituted by lower alkyl, and R′ being independently selected from hydrogen and lower alkyl;
• X is —CH2—;
• and
• n is 0, 1, 2, 3 or 4;
• or a pharmaceutically acceptable acid addition salt thereof.