Antibiotics AW998A, AW998B, AW998C and AW998D
AssigneeWyeth Holdings Corporation
InventorsFangming Kong, Guy Thomas Carter, Scott William Luckman
Life of this patent
Estimating the term…
Abstract
This invention relates to antibiotics selected from the group AW998A, AW998B, AW998C and AW998D derived from the microorganism Streptomyces designated LL-AW998, which are useful as antibacterial agents.
Claims9
The compound AW998A which has the structure:
The compound AW998B which has the structure:
The compound AW998C which has the structure:
The compound AW998D which has the structure:
A method of treating a warm-blooded animal affected by bacterial infections, which method comprises administering to said warm-blooded animal in need thereof an effective amount of a compound selected from the group AW998A, AW998B, AW998C and AW998D or combinations thereof.
A pharmaceutical composition comprising an effective amount of a compound selected from the group AW998A, AW998B, AW998C and AW998D or combinations thereof together with one or more pharmaceutically acceptable carriers.
A process for the preparation of a compound selected from the group AW998A, AW998B, AW998C and AW998D or combinations thereof which comprises cultivating Streptomyces designated LL-AW998 under aerobic conditions, in a sterile liquid medium containing assimilable sources of carbon, nitrogen and inorganic anion and cation salts, until substantial antibiotic activity is imparted to said medium by the production of a compound selected from the group AW998A, AW998B, AW998C and AW998D, or combination thereof, recovering and isolating compounds selected from the group AW998A, AW998B, AW998C and AW998D or combinations thereof.
A disinfectant composition comprising an effective amount of a compound selected from the group AW998A, AW998B, AW998C and AW998D or combinations thereof together with one or more acceptable disinfectant carriers.
Dependencies are inferred from the claim text.