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US 7,018,839 B2Granted
Peptide from soluble form of acetylcholinesterase, active as a calcium channel modulator
AssigneeSynaptica Limited
InventorsSusan Adele Greenfield, David John Talbutt Vaux
Life of this patent
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Abstract
The acetylcholinesterase 14-mer peptide AEFHRWSSYMVHWK acts alone or in synergism with 2-amyloid to contribute to neuronal degeneration, e.g. in Parkinson's and Alzheimer's diseases, perhaps by exerting calcium channel opening activity. Antibodies and other compounds which inhibit the biological activity are useful for prophylaxis or treatment.
Claims5
An isolated peptide consisting of a peptide of SEQ ID No. 1, said peptide having a calcium channel modulatory function.
Dependencies are inferred from the claim text.