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AssigneeCellectricon AB
InventorsOwe Orwar, Mattias Karlsson, Daniel Chiu, Anette Stromberg, Anders Karlsson
Estimating the term…
An apparatus and method are disclosed for electromanipulation of at least one cell or cell-like structure having cell-like membranes, the method comprising the steps: (a) at least one cell or cell-like structure is transported from one or more sample containers located on a chip through microchannel(s) located on said chip into a chamber located on said chip, wherein said chamber contains electrode(s) connected to a voltage generator, wherein said microchannel provides a fluid contact between the sample containers, (b) said cell or cell-like structure(s) is placed close to said at least one electrode, and (c) an electrical field is applied and focused on said cell or cell-like structure(s), said electrical field being of a strength sufficient to obtain pore-formation or fusion of said at least one cell or cell-like structure with another cell or cell-like structure(s) present in said chamber.
A method for electromanipulation of at least one cell or cell-like structure having cell-like membranes, comprising the following consecutive steps:
An apparatus for electromanipulation of at least one cell or cell-like structure having cell-like membranes, said apparatus comprising one or more sample containers for said cell or cell-like structure in fluid contact through at least one microchannel with a fusion chamber, optical trapping means for transport of individual cells or cell-like structures through said at least one microchannel into the fusion chamber, and at least one microelectrode connected to a voltage generator for providing a focused electrical field in the fusion chamber, wherein said sample container, said microchannel and said fusion chamber are placed on a chip.
Dependencies are inferred from the claim text.