Influenza sensor
AssigneeThe Regents of the University of California
InventorsBasil I. Swanson, Xuedong Song, Clifford Unkefer, Louis A. Silks, III, Jurgen G. Schmidt
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Abstract
A sensor for the detection of tetrameric multivalent neuraminidase within a sample is disclosed, where a positive detection indicates the presence of a target virus within the sample. Also disclosed is a trifunctional composition of matter including a trifunctional linker moiety with groups bonded thereto including (a) an alkyl chain adapted for attachment to a substrate, (b) a fluorescent moiety capable of generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, the recognition moiety capable of binding with tetrameric multivalent neuraminidase.
Claims2
A trifunctional composition of matter comprising:
- a trifunctional linker moiety including as groups bonded thereto (a) an alkyl chain for attachment to a substrate, (b) a fluorescent moiety for generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, said recognition moiety having a binding affinity with tetrameric multivalent neuramimidase.
Dependencies are inferred from the claim text.