Diagnostics and therapeutics for macular degeneration-related disorders
AssigneeUniversity of Iowa Research Foundation
InventorsGregory S. Hageman, Robert F. Mullins
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Abstract
The invention relates to methods for diagnosing and treating macular degeneration-related disorders. The invention also related to methods for identifying genes that cause macular degeneration-related disorders.
Claims12
A method for diagnosing, or identifying a predisposition to the development of a macular degeneration related disorder in a subject, comprising detecting in a biological sample from the subject the presence or abnormal levels of an autoantibody against, or an immune complex containing, fibulin-3, beta-crystallin A2, beta-crystallin A3, beta-crystallin A4, beta-crystallin S, calreticulin, 14-3-3 protein epsilon, or serotransferrin or an antigenic fragment thereof.
Dependencies are inferred from the claim text.