Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors

An implantable biocompatible sensor device comprising:

• a first sensor body configured for chronic in viva implantation proximate a tumor site in a subject and to output data corresponding to at least one predetermined parameter and a transmitter coil and associated electronic components configured for wireless transmittal of the sensor output data to a spatially remote receiver, wherein the first sensor body comprises a radiation sensor element with a MOSFET-based radiation detection circuit, the radiation detection circuit being configured to provide MOSFET-based radiation data corresponding to detected radiation delivered to the subject in an oncology therapeutic treatment;
• and
• a second sensor body having at least one sensor element configured for in vivo implantation at a location that is spaced apart from the first sensor body, the second sensor body configured to output data corresponding to at least one sensed internal predetermined parameter, the second sensor body comprising a transmitter coil and associated electronic components configured for wireless transmittal of the sensor output data to the spatially remote receiver.

An implantable oncology sensor, comprising:

• a chronically implantable biocompatible sensor body configured to be implanted in vivo, the sensor body comprising a radiation detection circuit that is configured to provide MOSFET-based radiation exposure data, and electronics for wirelessly communicating with an external reader, wherein the radiation detection circuit is configured during an ionizing radiation exposure and inductively powered to wirelessly transmit radiation exposure data at a desired evaluation time.

An oncology medical kit comprising:

• a plurality of discrete sterilized chronically implantable sensors for oncology patients, the implantable sensors having a biocompatible sensor body and are configured to wirelessly communicate with a common external reader, wherein the implantable sensors are inductively powered, wherein a plurality of the sensors are configured to remain concurrently implanted and operative in a patient over an oncology treatment period, and wherein the sensors comprise a MOSFET-based radiation detection circuit in the sensor body configured to detect radiation associated with oncology treatments received in vivo.