Method for the 1,3 dipolar cycloaddition of organic compounds in a microreactor
AssigneeMerck Patent GmbH
InventorsHanns Wurziger, Joeran Stoldt, Guido Pieper, Norbert Schwesinger
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Abstract
The invention relates to a method for the 1,3 dipolar cycloaddition of organic compounds, characterized in that the reaction is carried out in a microreactor.
Claims22
A method for the 1,3-dipolar cycloaddition of an organic compound, comprising mixing at least one organic compound in liquid or dissolved form with at least one dipolarophile in liquid or dissolved form in at least one static micromixer connected via an outlet to a capillary, and reacting for a residence time wherein the reaction mixture flows through the microreactor at a flow rate of 0.01 –100 ml/min, and optionally isolating the formed organic cycloaddition product from the reaction mixture.
Dependencies are inferred from the claim text.