Low-substituted hydroxypropyl cellulose and agent serving both as binder and disintegrant for dry direct compression
AssigneeShin-Etsu Chemical Co., Ltd.
InventorsNaosuke Maruyama, Hiroshi Umezawa
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Abstract
Provided is an agent serving as a binder and a disintegrant for dry direct compression having a high binding property and fluidity. More specifically, provided are low-substituted hydroxypropyl cellulose having coiled fibers; an agent serving both as a binder and a disintegrant for dry direct compression and a solid preparation, each comprising the low-substituted hydroxypropyl cellulose; and a process for producing the low-substituted hydroxypropyl cellulose having coiled fibers.
Claims13
Low-substituted hydroxypropyl cellulose having coiled fibers and having a molar substitution of the hydroxypropoxyl groups ranging from 0.1 to 0.5.
A process for producing low-substituted hydroxypropyl cellulose having coiled fibers, comprising granulating, in a kneader, a washed product of low-substituted hydroxypropyl cellulose having a molar substitution of hydroxypropoxyl groups ranging from 0.1 to 0.5.
Dependencies are inferred from the claim text.