Isolated peptides which bind to HLA-C molecules and uses thereof
AssigneesLudwig Institute for Cancer Research, Cornell Research Foundation, Inc., Memorial Sloan Kettering Cancer Center
InventorsSacha Gnjatic, Lloyd J. Old, Yasuhiro Nagata, Elke Jager, Yao-Tseng Chen, Alexander Knuth
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Abstract
The invention teaches peptide epitopes which bind to HLA-Cw3 and HLA-Cw6 molecules on the surface of cells. The peptides are useful diagnostically and therapeutically, as are DNA molecules which encode them, and the cytolytic T lymphocytes specific to the HLA/peptide complexes. Also a feature of the invention is a method for identifying relevant molecules such as those described herein, in a system that uses stimulation and restimulation using different viral vectors.
Claims5
An isolated peptide consisting of an amino acid sequence as set forth in SEQ ID NO:
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Dependencies are inferred from the claim text.