Agents for intravitreal administration to treat or prevent disorders of the eye
AssigneeVitreo-Retinal Technologies, Inc.
InventorDavid Castillejos
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Abstract
Methods and preparatons for treating disorders of the eye and/or causing posterior vitreous disconnection or disinsertion. Preparations containing a) urea, b) urea derivatives (e.g., hydroxyurea, thiourea), c) a non-steroidal anti-inflamatory agents, d) antmetabolites, e) urea, urea derivatives, non-enzymatic proteins, nucleosides, nucleotides and their derivatives (e.g., adenine, adenosine, cytosine, cytadine, guanine, guanitadine, guanidinium, thymidine, thimitadine, uradine, uracil, cystine), uric acid, calcium acetal salicylate, ammonium sulfate or other compound capable of causing non-enzymatic dissolution of the hyaloid membrane or e) any of the possible combinations thereof, are administered to the eye in therapeutically effective amounts.
Claims12
A method for causing liquefaction of the vitreous humor in the eye of a human or veterinary patient, said method comprising the step of:
- A. delivering into the posterior segment of the eye a therapeutically effective amount of an agent that comprises urea or a urea derivative or mixtures thereof.
Dependencies are inferred from the claim text.