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US 7,008,920 B2Granted
Medicinal composition
AssigneeOtsuka Pharmaceutical Co., Ltd.
InventorsToshikiro Kimura, Kazutaka Higaki, Masateru Miyake, Takanori Minami
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AssigneeOtsuka Pharmaceutical Co., Ltd.
InventorsToshikiro Kimura, Kazutaka Higaki, Masateru Miyake, Takanori Minami
Estimating the term…
The present invention provides a medicinal composition comprising (1) a pharmacologically active substance, (2) a drug absorbefacient and (3) a taurine compound or a polyamine. A taurine compound has an efect of suppressing or preventing damage of the intestinal mucous membrane, and therefore adding the taurine compound to a medicinal composition containing a pharmacologically active substance and a drug absorbefacient makes it possible to suppress or prevent damage of the intestinal mucosa. A polyamine improves the absorbability of pharmacologically active substances, and therefore adding the polyamine to a medicinal composition containing a pharmacologically active substance and a drug absorbefacient makes it possible to decrease the dose of the drug absorbefacient, thereby suppressing or preventing damage of the intestinal mucosa.
A medicinal composition comprising a pharmacologically active substance, a drug absorbefacient and a polyamine.
A method for improving absorption of a pharmacologically active substance, the method comprising adding a polyamine to a medicinal composition containing the pharmacologically active substance and a drug absorbefacient.
A method for suppressing or preventing damage of the intestinal mucosa, the method comprising adding a polyamine to a medicinal composition containing a pharmacologically active substance and a drug absorbefacient.
A method for improving absorption of a pharmacologically active substance, the method comprising administering to a patient in need thereof, a medicinal composition comprising the pharmacologically active substance and a drug absorbefacient in combination with a drug absorption enhancer comprising a polyamine.
A method for suppressing or preventing damage of the intestinal mucosa, the method comprising administering to a patient in need thereof, a medicinal composition comprising a pharmacologically active substance and a drug absorbefacient in combination with a drug absorption enhancer comprising a polyamine.
A method for suppressing or preventing damage of the intestinal mucosa caused by administration of a medicinal composition containing a pharmacologically active substance and a drug absorbefacient, the method comprising administering to a patient in need thereof, a polyamine.
Dependencies are inferred from the claim text.