Method and composition for an early vaccine to protect against both common infectious diseases and chronic immune mediated disorders or their sequelae
AssigneeClassen Immunotherapies, Inc.
InventorJohn Barthelow Classen
Life of this patent
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Abstract
A method of immunization, and compositions therefor, are provided for substantially preventing or reducing the symptoms of at least one infectious disease and at least one chronic immune mediated disorder. An immunogenic challenge which supplements the normal childhood immunization schedule can help ensure the proper maturation of the immune system and prevent the development of chronic immune mediated disorders, such as immune-mediated diabetes or SLE.
Claims213
A method for safely immunizing a human with one or more doses of one or more immunogens which induce protective immunity to one or more infectious diseases when administered according to one or more immunization schedules, said method comprising
- (I) considering the association between said immunization schedule and one or more chronic immune mediated disorders by a) considering the incidence, prevalence or frequency of a chronic immune mediated disorder in a first group comprising humans where the majority receive an immunization schedule comprising said one or more immunogens relative to that in at least one other group comprising humans where the majority receive a different immunization schedule, or b) considering the risk of said chronic immune mediated disorder associated with said immunization schedule relative to at least one other immunization schedule of said one or more immunogens
- (II) screening one or more potential recipients and identifying at least one human subject who would be expected to be immunized safely with said one or more immunogens according to said immunization schedule reflective of the analysis from (I), and
- (III) immunizing said human against said one or more infectious disease by a method identified in (I).
Dependencies are inferred from the claim text.