Method and apparatus for producing dry particles
AssigneeAdvanced Inhalation Research, Inc.
InventorsRichard P. Batycky, Blair C. Jackson, Lloyd P. Johnston, Jeffrey D. Mintzes, Ernest E. Penachio
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Abstract
Method and apparatus for producing dry particles. Two liquid components are combined in a static mixer, atomized into droplets, and the droplets dried to form dry particles. Use of the static mixer enables incompatible liquid components to be rapidly and homogeneously combined. The present invention optimizes process conditions for increasing and controlling particle porosity. The present invention also allows for optimization of particle size in real-time during particle production.
Claims6
A method for preparing a dry powder composition, comprising:
- combining a first phase and a second phase in a static mixer to form a combination wherein the first phase comprises human growth hormone and sodium phosphate, and the second phase comprises ethanol and ammonium bicarbonate;
- atomizing the combination to produce droplets;
- and
- drying the droplets to form dry particles.
Dependencies are inferred from the claim text.