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US 7,008,591 B2Granted
Supercritical fluid extraction process for tissue preparation
AssigneeEdwards Lifesciences Corporation
InventorsRalph Kafesjian, Myron Howanec, Jr.
Life of this patent
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Abstract
The present invention provides methods for preparing tissue for incorporation into xenografts and bioprosthetic devices. The methods of the invention make use of supercritical fluids to remove infectious materials and chemical agents from tissues, as well as to permeate a tissue with a chemical agent (e.g. tanning, cross-linking, and bioactive agents).
Claims36
A method of removing prions from mammalian soft-tissue, said method comprising subjecting said soft-tissue to extraction with a medium comprising a supercritical fluid, thereby removing said prions.
Dependencies are inferred from the claim text.