Porous hydroxy apatite containing silicon and magnesium, and a preparation method thereof
AssigneesKorea Institute of Ceramic Engineering and Technology, Meta Biomed Co., Ltd.
InventorsSoo-Ryong Kim, Young Hee Kim, Yoon Joo Lee, Hae-Jung Kim, Sang-Jin Jung, Hee Song
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Abstract
Disclosed are a silicon- and magnesium-containing porous hydroxyapatite, and a preparation method thereof which comprises the steps of performing a hydrothermal treatment of a natural coral and performing a solvothermal treatment.
Claims7
A silicon- and magnesium-containing porous hydroxyapatite, comprising three-dimensionally connected pores in size of 200–500 μm and having substantially a human cancellous bone structure, and comprising silicon and magnesium ions in an amount of 0.05–5 wt %, respectively.
A preparation method of a silicon- and magnesium-containing porous hydroxyapatite, comprising the steps of:
- (1) performing a hydrothermal treatment of a coral sample pre-treated with a NaOCl solution in an aqueous (NH4)2HPO4 solution;
- and
- (2) performing a solvothermal treatment of the coral sample prepared in step (1) in a saturated solution of silicon acetate in acetone, to obtain the silicon- and magnesium-containing porous hydroxyapatite,
- wherein the coral sample comprises magnesium ions.
A silicon- and magnesium-containing porous hydroxyapatite used for an artificial bone including a spine or long bone, an orbital implant, or a chin implant, comprising three-dimensionally connected pores in size of 200–500 μm, and having substantially a human cancellous bone structure, and comprising silicon and magnesium ions in an amount of 0.05–5 wt %, respectively.
Dependencies are inferred from the claim text.