Method for the determination of glycated hemoglobin

A method of assaying glycated hemoglobin in a sample, comprising:

• electrochemically determining a total amount of hemoglobin in a blood, blood-containing, or blood-derived sample;
• spectrophotometrically determining an amount of glycated hemoglobin in the sample;
• and
• determining the amount of glycated hemoglobin relative to the total amount of hemoglobin in the sample.

A method of assaying glycated hemoglobin in a sample, comprising:

• electrochemically determining a total amount of hemoglobin in a blood, blood-containing, or blood-derived sample;
• separating glycated hemoglobin from the sample and from non-glycated hemoglobin to form a second sample;
• determining an amount of glycated hemoglobin in the second sample;
• and
• determining the amount of glycated hemoglobin relative to the total amount of hemoglobin in the sample.

A method of assaying glycated hemoglobin in a sample, comprising:

• electrochemically determining a total amount of hemoglobin in a blood, blood-containing, or blood-derived sample, by exposing the sample to an enzyme associated with a cathode, determining an amount of oxygen in the sample via an enzymatic redox reaction, and determining the total amount of hemoglobin in the sample from the amount of oxygen;
• determining an amount of glycated hemoglobin in the sample;
• and
• determining the amount of glycated hemoglobin relative to the total amount of hemoglobin in the sample.

A method of assaying glycated hemoglobin in a sample, comprising:

• electrochemically determining a total amount of hemoglobin in a blood, blood-containing, or blood-derived sample;
• separating glycated hemoglobin from the sample to form a second sample;
• spectrophotometrically determining an amount of glycated hemoglobin in the second sample;
• and
• determining the amount of glycated hemoglobin relative to the total amount of hemoglobin in the sample.

A method of assaying glycated hemoglobin in a sample, comprising:

• electrochemically determining a total amount of hemoglobin in a blood, blood-containing, or blood-derived sample;
• separating glycated hemoglobin from the sample and from non-glycated hemoglobin to form a second sample;
• spectrophotometrically determining an amount of glycated hemoglobin in the second sample;
• and
• determining the amount of glycated hemoglobin relative to the total amount of hemoglobin in the sample.

A method of assaying glycated hemoglobin in a sample, comprising:

• electrochemically determining a total amount of hemoglobin in a blood, blood-containing, or blood-derived sample;
• separating glycated hemoglobin from non-glycated hemoglobin to form a second sample;
• determining an amount of glycated hemoglobin in the second sample via direct oxidation or enzymatic electrooxidation;
• and
• determining the amount of glycated hemoglobin relative to the total amount of hemoglobin in the sample.