Antibodies to secreted protein HEMCM42
AssigneeHuman Genome Sciences, Inc.
InventorsSteven M. Ruben, Craig A. Rosen, Gregory A. Endress
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Abstract
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
Claims26
An isolated antibody or fragment thereof that specifically binds to a protein selected from the group consisting of:
- (a) a protein consisting of amino acid residues 1 to 113 of SEQ ID NO:59,
- (b) a protein consisting of amino acid residues 30 to 113 of SEQ ID NO:59,
- (c) a protein consisting of a portion of SEQ ID NO:59, wherein said portion comprises at least 30 contiguous amino acid residues of SEQ ID NO:59, and
- (d) a protein consisting of a portion of SEQ ID NO:59, wherein said portion comprises at least 50 contiguous amino acid residues of SEQ ID NO:59.
An isolated monoclonal antibody or fragment thereof that specifically binds to a protein selected from the group consisting of:
- (a) a protein consisting of amino acid residues 1 to 113 of SEQ ID NO:59,
- (b) a protein consisting of amino acid residues 30 to 113 of SEQ ID NO:59,
- (c) a protein consisting of a portion of SEQ ID NO:59, wherein said portion comprises at least 30 contiguous amino acid residues of SEQ ID NO:59, and
- (d) a protein consisting of a portion of SEQ ID NO:59, wherein said portion comprises at least 50 contiguous amino acid residues of SEQ ID NO:59.
Dependencies are inferred from the claim text.