Monoclonal antibodies directed against the G3BP protein, and uses
AssigneeAventis Pharma S.A.
InventorsFabienne Parker, Mireille Kenigsberg, Marc Duchesne, Isabelle Barlat
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Abstract
The invention concerns monoclonal antibodies directed against the G3BP protein and cell lines producing them. The invention also concerns the use of said antibodies or their derivatives for obtaining medicines and diagnostic reagents.
Claims5
The antibody Mab 1F1, secreted by the hybridoma line G3BP 1F1 1D1 deposited on 9 Jun. 1998 at the C.N.C.M. under the number I-2038.
Hybridoma line G3BP 1 F1 1 D1 deposited on 9 Jun. 1998 at the C.N.C.M. under the deposit number I-2038.
Monoclonal antibody directed against the protein of SEQ ID NO:1 and capable of inducing apoptosis in various types of tumor cells, wherein the antibody recognizes an epitope between amino acids 22–34 of SEQ ID NO:1.
Dependencies are inferred from the claim text.