Peptide derivatives
AssigneeChugai Seiyaku Kabushiki Kaisha
InventorsTakuya Shiraishi, Shojiro Kadono, Masayuki Haramura, Haruhiko Sato, Toshiro Kozono, Takaki Koga, Akihisa Sakamoto
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AssigneeChugai Seiyaku Kabushiki Kaisha
InventorsTakuya Shiraishi, Shojiro Kadono, Masayuki Haramura, Haruhiko Sato, Toshiro Kozono, Takaki Koga, Akihisa Sakamoto
Estimating the term…
A compound of Formula (1): wherein R1 represents an amidinophenyl group, etc.; R2 represents a hydrogen atom, etc.; R3 represents a carbamoylalkyl group, etc.; R4 represents a hydrogen atom, etc.; R5 represents a benzyl group, etc.; R6 represents a hydrogen atom, etc.; and R7 represents an alkylsulfonyl group, etc. A crystal of a complex between factor VIIa/human soluble tissue factor and a low-molecular weight reversible factor VIIa inhibitor. A medium carrying a part or all of structure coordinate data of a complex between human factor VIIa/human soluble tissue factor and a low-molecular weight reversible factor VIIa inhibitor, obtainable by X-ray crystal structure analysis of the crystal. A method for computationally designing a low-molecular weight reversible factor VIIa inhibitor using the coordinate data.
A compound of Formula (1):
Dependencies are inferred from the claim text.