Glucose transporter/sensor protein and uses thereof

A method for determining whether a subject has a defect in cell proliferation comprising assaying a diagnostic sample of the subject for GLUTx expression wherein detection of GLUTx expression elevated above normal is diagnostic of a defect in cell proliferation, wherein the defect in cell proliferation is a mammary adenocarcinoma or an endometrial adenocarcinoma, wherein GLUTx protein consists of the amino acid sequence set forth in SEQ ID NO:1, and wherein the diagnostic sample is assayed using at least one nucleic acid probe that specifically hybridizes to nucleic acid encoding GLUTx.

A method for assessing the efficacy of therapy to treat a defect in cell proliferation in a subject who has undergone or is undergoing treatment for a defect in cell proliferation, comprising assaying a diagnostic sample of the subject for GLUTx expression, wherein detection of GLUTx expression elevated above normal in the diagnostic sample is indicative of a need to continue therapy to treat the defect in cell proliferation, and normal GLUTx expression in the diagnostic sample is indicative of successful therapy, wherein the defect in cell proliferation is a mammary adenocarcinoma or an endometrial adenocarcinoma, and wherein GLUTx protein has the amino acid sequence set forth in SEQ ID NO:1.