RIP3 associated cell cycle protein
AssigneeRiegel Pharmaceuticals, Inc.
InventorsYing Luo, PeiWen Yu, Mary Shen, Betty Huang
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Abstract
The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
Claims5
A recombinant cell cycle protein comprising an amino acid sequence with 95% identity to SEQ ID NO:2, wherein the protein binds to Receptor-Interacting Protein 3 (RIP3).
Dependencies are inferred from the claim text.