Chemokine receptor obtained from a cDNA library of fetal liver-spleen
AssigneeNuvelo, Inc.
InventorsJohn Ford, George Yeung
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Abstract
The invention provides novel polynucleotides isolated from cDNA libraries of human fetal liver-spleen and fetal liver as well as polypeptides encoded by these polynucleotides. The polypeptide is a human chemokine receptor that is a member of a family of G protein-coupled receptors characterized by seven transmembrane domains. Other aspects of the invention include vectors containing polynucleotides of the invention and related host cells as well a processes for producing chemokine receptor polypeptides, and antibodies specific for such polypeptides.
Claims6
An antibody or antibody fragment thereof that specifically binds to a transmembrane polypeptide consisting of the amino acid sequence of SEQ ID NO:
- 3.
An antibody or antibody fragment thereof that specifically binds to a transmembrane polypeptide encoded by the polynucleotide of SEQ ID NO:2.
Dependencies are inferred from the claim text.