Protein having PDZ domain sequence
AssigneeChugai Seiyaku Kabushiki Kaisha
InventorsShin-Ichi Funahashi, Shoji Miyata
Life of this patent
Estimating the term…
Abstract
While analyzing changes in gene expression by TNFα in umbilical vascular endothelial cells, a gene showing enhanced expression due to stimulation with TNFα was isolated. After screening with this gene as a probe, a gene encoding a protein was isolated. Analysis of the protein encoded by this isolated gene revealed that this novel protein has never been reported and has a PDZ domain in its molecule that plays an important role in protein—protein interactions.
Claims8
A substantially pure polypeptide comprising the amino acid sequence of SEQ ID NO:1.
A substantially pure polypeptide comprising the amino acid sequence of SEQ ID NO:2.
Dependencies are inferred from the claim text.