Physiological tissue repair and functional organ regeneration by cultivation of regenerative stem cells in vivo and in situ
AssigneeRongxiang Xu
InventorRongxiang Xu
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Abstract
The present invention provides novel compositions and methods for pharmaceutical or nutraceutical use in an animal, preferably in a human. In one aspect, compositions and methods are provided for promoting cell growth, tissue repair and organ regeneration, preferably in vivo and in situ. The composition comprises a sterol compound dissolved in oil at a concentration at least 0.5% by weight. The compositions may be used in the treatment of various conditions caused by injury, diseases and aging. As shown clinically, the methodology disclosed in the present invention was used successfully to regenerate or clone a new organ through cultivation of regenerative stem cells in vivo and in situ.
Claims37
A method for regenerating skin with normal physiological structure at a wound site of the skin in a mammal comprising:
- administering in vivo to said mammal at the site of the wound a composition comprising
- beeswax at a concentration of 1%–20% by weight and a fatty acid-containing oil at a concentration of at least 10% by weight based on the total weight of the composition;
- and a sterol compound added to and dissolved in said oil at a concentration of at least 1% by weight based on the total weight of the composition, such that keratin-19 expressing keratinocytes are activated at the wound site to regenerate the skin with normal physiological structure.
Dependencies are inferred from the claim text.