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US 6,962,807 B2Granted
Descendants of bacteria devoid of N terminal formylation useful for the production of proteins and peptides
OwnerPhilippe Marliere, Rupert Mutzel +1inventors
InventorsPhilippe Marliere, Rupert Mutzel, Didier Mazel
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Abstract
The present invention relates to producing non-formylated proteins and/or peptides in bacterial cells lacking deformylase and/or transformylase.
Claims20
A bacterial cell which is Escherichia coli that has been deleted for the fmt (Met-tRNA transformylase) gene or both the def (deformylase) and fmt (Met-tRNA transformylase) genes from the def-fmt operon,
- wherein said bacterial cell expresses non-formylated proteins, polypeptides or peptides.
Dependencies are inferred from the claim text.