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US 6,960,467 B2Granted
Biochannel assay for hybridization with biomaterial
AssigneeClinical Micro Sensors, Inc.
InventorsChan-Long Shieh, Barbara Foley, Huinan Yu, Vi-En Choong
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Abstract
The invention relates to a microfluidic device with microchannels that have separated regions which have a member of a specific binding pair member such as DNA or RNA bound to porous polymer, beads or structures fabricated into the microchannel. The microchannels of the invention are fabricated from plastic and are operatively associated with a fluid propelling component and detector.
Claims24
A microfluidic device comprising:
- (i) a first microchannel comprising a plurality of spatially distinct regions upon which a member of a specific binding pair is immobilized;
- (ii) at least a first entrance port and at least a first exit port for the transportation of at least one test sample;
- (iii) a fluid propelling component that controls that flow rate of said test sample;
- and
- (iv) a recirculating arm for recirculating said test sample across a spatially distinct regions.
2 more elements
Dependencies are inferred from the claim text.