Back to results
US 6,958,359 B1Granted
Vanadium compounds as anti-angiogenic agents
AssigneeParker Hughes Institute
InventorFatih M. Uckun
Life of this patent
Estimating the term…
Abstract
Vanadium compounds for inhibiting angiogenesis useful for treating or preventing diabetic retinopathy, hemangiomas, cancers with abnormal blood vessel supply, restenosis following vascular injury, and the like.
Claims39
A method for inhibiting angiogenesis in a non-cancerous tissue comprising administering to a subject in need of treatment an effective angiogenesis inhibiting amount of a vanadium compound having the following structure:
- wherein
- R1 and R2 are each independently a monodentate ligand or together form a bidentate ligand;
- and
- R3 and R4 are each independently a cyclopentadienyl ring, wherein each cyclopentadienyl ring is optionally substituted with one or more (C1-C3)alkyl.
1 more element
Dependencies are inferred from the claim text.