Method of enhancing catheter patency using a citrate salt catheter lock solution
AssigneeAsh Access Technology, Inc.
InventorStephen R. Ash
Life of this patent
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Abstract
This invention relates to an infusion device for a catheter lock solution, to a method of enhancing the patency of catheters in animals and to a catheter lock solution. The device includes a syringe (34) containing a lock solution comprising a citrate salt. The method for enhancing the patency of catheters includes infusing a lumen (14, 16) of an indwelling catheter (10) with a lock solution comprising a citrate salt. In one aspect of the invention, the catheter lock solution includes a citrate salt and a viscosifying agent. The lock solution is prepared to have sufficient viscosity and density to remain in the lumen for a desired amount of time.
Claims35
A method for treating a patient, comprising:
- selecting a patient having an indwelling intravascular catheter defining a lumen therethrough and having an infection or a substantial risk of infection related to the presence of the catheter;
- and
- infusing a catheter lock solution into the lumen, the solution comprising a citrate salt solution having a concentration effective to eliminate infection and to reduce the likelihood of subsequent infection;
- wherein the lock solution comprises a citrate salt in a concentration range, in weight percent, of between about 10% and about 40%.
A method of inhibiting infections in an animal having an indwelling catheter defining at least one lumen therethrough, said method comprising infusing into the lumen a pharmaceutically acceptable lock solution including a compound having anticoagulant and antibiotic activity, wherein said lock solution has a density of between about 1.0 g/ml and about 1.5 g/ml and a viscosity of between about 1.5 cP and about 4.0 cP.
A method of treating animals having a surgically implanted catheter, said method comprising infusing into said catheter a pharmaceutically acceptable lock solution comprising a bactericidal component, said bactericidal component including greater than about 50%, by weight based on the weight of the bactericidal component, of a citrate salt.
A method for treating a patient, comprising:
- selecting a patient having an indwelling intravascular catheter defining a lumen therethrough, and needing a bactericidal catheter lock solution;
- and
- infusing a catheter lock solution into the lumen, the solution comprising a bactericidal component;
- wherein the bactericidal component consists essentially of sodium citrate dissolved in the solution.
A method for treating a patient, comprising:
- selecting a patient that has an indwelling intravascular catheter defining a lumen therethrough and that has a need for infusion of a bactericidal catheter lock solution into the lumen of the catheter;
- and
- responding to the need by infusing into the lumen a catheter lock solution comprising a citrate salt solution having a concentration effective to eliminate infection and to reduce the likelihood of subsequent infection.
Dependencies are inferred from the claim text.