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US 6,953,575 B2Granted
Methods of treating central nervous system disorders using viral vectors
AssigneesAvigen, Inc., The Regents of the University of California
InventorsKrys Bankiewicz, Janet Cunningham, Jamie L. Eberling
Life of this patent
Estimating the term…
Abstract
Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
Claims7
A method of delivering recombinant adeno-associated virus virions to the brain of a subject suffering from a central nervous system (CNS) disorder, comprising:
- (a) providing a composition comprising recombinant adeno-associated virus virions, said recombinant adeno-associated virus virions encoding a protein;
- and
- (b) administering said composition to the brain of the subject such that distribution of said recombinant adeno-associated virus virions over an area greater than 5 mm2 is achieved, wherein said recombinant adeno-associated virus virions are administered by convection enhanced delivery using a pump.
Dependencies are inferred from the claim text.