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US 6,948,497 B2Granted
Breathing gas delivery method and apparatus
AssigneeRIC Investments, LLC
InventorsRonald J. Zdrojkowski, Mark H. Sanders, Mark Estes
Life of this patent
Estimating the term…
Abstract
An improved methodology and systems for delivery of breathing gas such as for the treatment of obstructive sleep apnea through application of alternating high and low level positive airway pressure within the airway of the patient with the high and low airway pressure being coordinated with the spontaneous respiration of the patient, and improved methods and apparatus for triggering and for leak management in such systems.
Claims28
A pressure support system comprising:
- a pressure generating system adapted to generate a flow of breathing gas;
- a patient circuit having a first end coupled to an outlet of the pressure generating system and a second end;
- a patient interface device coupled to the second end of the patient circuit;
- a sensor operatively coupled to the pressure generating system or the patient circuit so as to monitor patient breathing;
- processing means, operatively coupled to the sensor and the pressure generating system, for (1) causing the pressure generating system to apply the flow of breathing gas to an airway of a patient at an inspiratory positive airway pressure during at least a portion of an inspiratory phase, wherein the inspiratory positive airway pressure is provided at a level relative to an ambient atmospheric pressure that is sufficient to prevent airway obstruction during at least a portion of such a patient's inspiratory breathing cycle, and for (2) adjusting the pressure of the flow of gas in the patient's airway to synchronize the application of positive pressure to such a patient's airway with an occurrence of alternating inspiratory and expiratory phases of such a patient's respiration in a manner to maintain the positive pressure in the patient's airway during a sequence of the inspiratory and expiratory phases, with the magnitude of the positive pressure during at least a portion of each expiratory phase being less than the magnitude of the positive pressure during at least a portion of the immediately preceding inspiratory phase.
2 more elements
A method of treating obstructive sleep apnea comprising the steps of:
- providing a pressure support system adapted to generate a flow of breathing gas at a positive pressure greater than ambient atmospheric pressure;
- communicating the flow of breathing gas to an airway of such a patient via a patient circuit connected to the pressure support system;
- monitoring patient breathing;
- applying the flow of breathing gas to an airway of such a patient at an inspiratory positive airway pressure during at least a portion of an inspiratory phase at a pressure sufficient to prevent airway obstruction during at least a portion of such a patient's inspiratory breathing cycle;
- and
- adjusting the pressure of the flow of breathing gas in the patient's airway, based on monitoring patient breathing to coordinate the application of positive pressure to such a patient's airway with an occurrence of alternating inspiratory and expiratory phases of such a patient's respiration so as to maintain the positive pressure in such a patient's airway during a sequence of inspiratory and expiratory phases, with a magnitude of the positive pressure during at least a portion of each expiratory phase being less than a magnitude of the positive pressure during at least a portion of an immediately preceding inspiratory phase.
3 more elements
A method of treating obstructive sleep apnea comprising the steps of:
- providing a pressure support system adapted to generate a flow of breathing gas at a positive pressure greater than ambient atmospheric pressure;
- communicating the flow of breathing gas at the positive pressure to an airway of such a patient;
- adjusting the pressure of the flow of breathing as to coordinate with an occurrence of alternating inspiratory and expiratory phases of such a patient's respiration so as to maintain the positive pressure in such a patient's airway during a sequence of inspiratory and expiratory phases, with a magnitude of the positive pressure during at least a portion of each expiratory phase being less than a magnitude of the positive pressure during at least a portion of an immediately preceding inspiratory phase;
- maintaining the positive pressure in such a patient's airway during at least a portion of the inspiratory phase at a level sufficient to prevent airway obstruction;
- and
- identifying changes in such a patient's respiratory state between inspiration and expiration by monitoring patient breathing, determining a patient respiratory gas flow characteristic at selected time intervals to provide a plurality of gas flow characteristics displaced in time from one another based on the monitored breathing, identifying selected pairs of the respiratory gas flow characteristics from the plurality of gas flow characteristics displaced in time from one another, and comparing selected pairs of respiratory gas flow characteristics.
3 more elements
A method of treating obstructive sleep apnea comprising the steps of:
- providing a pressure support system adapted to generate a flow of breathing gas at a positive pressure greater than ambient atmospheric pressure;
- communicating the flow of breathing gas at the pressure to an airway of such a patient;
- adjusting the pressure of the flow of breathing gas to coordinate with an occurrence of alternating inspiratory and expiratory phases of such a patient's respiration so as to maintain the positive pressure in such a patient's airway during a sequence of inspiratory and expiratory phases, with a magnitude of the positive pressure during at least a portion of each expiratory phase being less than a magnitude of the positive pressure during at least a portion of an immediately preceding inspiratory phase;
- maintaining the positive pressure at such a patient's airway during at least a portion of the inspiratory phase at a level sufficient to prevent airway obstruction;
- and
- identifying changes in such a patient's respiratory state between inspiration and expiration by monitoring the flow of breathing gas to detect an instantaneous flow rate, processing the instantaneous flow rate to provide reference indicia, and comparing the instantaneous flow rate and the reference.
3 more elements
A method of treating obstructive sleep apnea comprising the steps of:
- providing a pressure support system adapted to generate a flow of breathing gas at a positive pressure greater than ambient atmospheric pressure;
- communicating the flow of breathing gas at the positive pressure to an airway of such a patient;
- adjusting the pressure of the flow of breathing as to coordinate with an occurrence of alternating inspiratory and expiratory phases of such a patient's respiration so as to maintain the positive pressure in such a patient's airway during a sequence of inspiratory and expiratory phases, with a magnitude of the positive pressure during at least a portion of each expiratory phase being less than a magnitude o the positive pressure during at least a portion of an immediately preceding inspiratory phase;
- maintaining the positive pressure in such a patient's airway during at least a portion of the inspiratory phase at a level sufficient to prevent airway obstruction;
- and
- determining a leak component of the flow of breathing gas by determining a rate of the flow of breathing gas, integrating the rate of the flow of breathing for a selected plurality of patient respiratory cycles to determine a total respiratory gas volume for the selected plurality of patient respiratory cycles, and dividing the total respiratory gas volume for the selected plurality of patient respiratory cycles by a time duration associated with the selected plurality of patient respiratory cycles.
3 more elements
A method of treating obstructive sleep apnea comprising the steps of:
- providing a pressure support system adapted to generate a flow of breathing gas at a positive pressure greater than ambient atmospheric pressure;
- communicating the flow of breathing gas at the positive pressure to an airway of a patient;
- adjusting the pressure of the flow of breathing gas to coordinate with an occurrence of alternating inspiratory and expiratory phases of such a patient's respiration so as to maintain the positive pressure in such a patient's airway during a sequence of inspiratory and expiratory phases, with a magnitude of the positive pressure during at least a portion of each expiratory phase being less than a magnitude of the positive pressure during at least a portion of an immediately preceding inspiratory phase;
- maintaining the positive pressure in such a patient's airway during at least a portion of the inspiratory phase at a level sufficient to prevent airway obstruction;
- measuring a total flow of the flow of breathing gas;
- measuring a pressure P(t) of the flow of breathing gas;
- calculating, based on the total flow and the pressure, a characteristic K of a hypothetical orifice, which represents an orifice through which all leakage of gas from the pressure support system occurs;
- and
- determining a total instantaneous flow of the leakage of gas from the pressure support system based on the characteristic K of the hypothetical orifice.
6 more elements
Dependencies are inferred from the claim text.