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US 6,942,965 B2Granted
Hepatitis A virus nucleotide sequences, recombinant proteins and uses thereof
AssigneeChiron Corporation
InventorsSergio Pichuantes, Steve H. Nguyen
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Abstract
Hepatitis A virus primers and probes derived from the capsid proteins and junction between the capsid precursor P1 and 2A of the HAV genome are disclosed. Also disclosed are nucleic acid-based assays using the primers and probes, antigen detection of HAV, and immunoassay for detecting the antibodies that bind to HAV.
Claims6
An isolated polynucleotide comprising:
- (a) a nucleotide sequence comprising the nucleotide sequence of SEQ ID NO:
- 15;
- (b) a sequence complementary to the sequence of (a);
- or
- (c) a fragment of either of the sequences in (a) or (b) wherein the fragment comprises at least 15 contiguous nucleotides of SEQ ID NO:
- 15 or of the complement of SEQ ID NO:
- 15.
4 more elements
Dependencies are inferred from the claim text.