Collagen/polysaccharide bilayer matrix
AssigneeDepuy Acromed, Inc.
InventorsRobert C. Spiro, Lin Shu Liu
Life of this patent
Estimating the term…
Abstract
Disclosed are bilayer matrices of a polysaccharide such as collagen (COL) and another polysaccharide such as hyaluronic acid (HA) with various COL/HA ratios. Each layer has a porous structure. These materials are useful for tissue regeneration, particularly when used with orthopedic implants and drug delivery.
Claims9
A multilayer biodegradable matrix for tissue regeneration, said matrix comprising two mechanically adhering layers, each of said layers comprising a cross-linked polymeric component selected from the group consisting of proteins, covalently cross-linked polysaccharides, and proteins covalently cross-linked to polysaccharides wherein each of said layers has a porosity sufficient to accommodate living cells therein.
Dependencies are inferred from the claim text.