Nanotechnology for drug delivery, contrast agents and biomedical implants
AssigneeNanoProducts Corporation
InventorsTapesh Yadav, Clayton Kostelecky
Life of this patent
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Abstract
A nanocomposite structure comprising a nanostructured filler or carrier intimately mixed with a matrix, and methods of making such a structure. The nanostructured filler has a domain size sufficiently small to alter an electrical, magnetic, optical, electrochemical, chemical, thermal, biomedical, or tribological property of either filler or composite by at least 20%.
Claims28
A biomedical material for administration in a human or animal comprising:
- nanostructured ceramic powders whose surface has been reacted with a precursor;
- a solid matrix;
- wherein the nanostructured ceramic powders have been embedded in the solid matrix;
- and
- wherein the nanostructured ceramic powders have a domain size smaller than a capillary blood vessel.
A biomedical material for administration in a human or animal comprising;
- nanostructured ceramic powders whose surface has been reacted with a precursor;
- a solid matrix;
- wherein the nanostructured ceramic powders have been embedded in the solid matrix;
- wherein the nanostructured ceramic powders have a domain size smaller than a capillary blood vessel;
- and a drug, wherein the nanostructured ceramic powders function as a carrier for the drug.
A biomedical material for administration in a human or animal comprising:
- nanostructured ceramic powders whose surface has been reacted with a precursor;
- a solid matrix;
- wherein the nanostructured ceramic powders have been embedded in the solid matrix;
- wherein the nanostructured ceramic powders have a domain size smaller than a capillary blood vessel;
- and
- a coating formed on the nanostructured ceramic powders wherein the nanostructured powders are water-soluble and the coated material is water-insoluble.
A biomedical material for administration in a human or animal comprising:
- nanostructured ceramic powders whose surface has been reacted with a precursor;
- a solid matrix;
- wherein the nanostructured ceramic powders have been embedded in the solid matrix;
- wherein the nanostructured ceramic powders have a domain size smaller than a capillary blood vessel;
- and
- wherein the material delivers a time-release drug.
A biomedical material for administration in a human or animal comprising:
- nanostructured ceramic powders whose surface has been reacted with a precursor;
- a solid matrix;
- wherein the nanostructured ceramic powders have been embedded in the solid matrix;
- wherein the nanostructured powders have a domain size smaller than a capillary blood vessel;
- and
- wherein the nanostructured ceramic powders are responsive to an externally applied magnetic field so as to preferentially gather and function in locations having an applied magnetic field.
A biomedical material for administration in a human or animal comprising:
- nanostructured ceramic powders whose surface has been reacted with a precursor;
- a solid matrix;
- wherein the nanostructured ceramic powders have been embedded in the solid matrix;
- wherein the nanostructured ceramic powders have a domain size smaller than a capillary blood vessel;
- and
- wherein the powders comprise a marker.
A biomedical material for administration in a human or animal comprising:
- a filler of powders whose surfaces have been reacted with a precursor;
- a solid matrix;
- wherein the filler of powders is embedded in the solid matrix;
- wherein the filler powders are nanostructured;
- the loading of the filler is less than 95 volume percent;
- and
- wherein the filler composition comprises a ceramic and the composition is administered in a human or animal.
A material for biological application comprising:
- nanostructured inorganic powders having a domain size smaller than 100 nm;
- wherein the surface of the nanostructured inorganic powders has been reacted with a precursor to form a coating;
- wherein the coating comprises a polymer and the coated nanostructured inorganic powders serve as a time-release delivery of a drug.
A biomedical material for administration in a human or animal comprising:
- nanostructured metallic powders whose surfaces have been reacted with a precursor;
- a solid matrix;
- wherein the nanostructured metallic powders are embedded in the solid matrix;
- a solid composite comprising a matrix and nanostructured metallic powders;
- and
- wherein the nanostructured metallic powders have a domain size smaller than a capillary blood vessel.
A nanostructured material comprising:
- water-soluble nanostructured inorganic powders having a domain size smaller than 100 nm;
- wherein the surfaces of the nanostructured inorganic powders have been reacted with a precursor;
- wherein the nanostructured inorganic powders become water-insoluble after the nanostructured inorganic powders have been reacted with the precursor.
A nanostructured material comprising:
- water-insoluble nanostructured inorganic powders having a domain size smaller than 100 nm;
- wherein the surfaces of the nanostructured inorganic powders have been reacted with a precursor;
- a coating on the powders, wherein the coating comprises a metallic species and the coated powders are a vehicle to deliver biologically active species;
- wherein the nanostructured inorganic powders becomes water-soluble after the nanostructured inorganic powders have been reacted with the precursor.
Dependencies are inferred from the claim text.