Compositions and methods for treatment of microbial infections
AssigneeImmunology Laboratories, Inc.
InventorsJiri Pillich, John Balcarek
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Abstract
The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The invention comprises administration of an effective amount of bacterial lysate compositions for the treatment of pathological conditions of microbial infections. The present invention can also be used to enhance the immune system to prevent infections by the administration of an effective amount of the compositions.
Claims12
A composition, comprising a bacterial lysate, wherein the bacterial lysate results from lysis of at least one bacterial strain by infection with at least one bacteriophage, wherein,
- (a) the at least one bacterial strain is a Staphylococcus aureus (S. aureus) strain deposited with the Czech Collection of Microorganisms (CCM) having accession numbers CCM 4992, CCM 4993, CCM 4994, CCM 4995, CCM 4996, CCM 4997, or CCM 4998;
- and,
- (b) the at least one bacteriophage is a bacteriophage deposited with the Deutsche Sammlung von Mikroorganismen und Zellkulturen GmBH (DSM) having accession number DSM 14614, DSM 14615, or DSM 14616.
A S. aureus bacterial strain deposited with the CCM under accession number CCM 4992, CCM 4993, CCM 4994, CCM 4995, CCM 4996, CCM 4997, or CCM 4998.
A method of treating S. aureus infections in humans or animals comprising administering to a human or animal having a pathological condition a composition comprising an effective amount of a bacterial lysate to induce an immune response, wherein the bacterial lysate results from lysis of at least one bacterial strain by infection with at least one bacteriophage, wherein,
- (a) the at least one bacterial strain is a Staphylococcus aureus (S. aureus) strain deposited with the Czech Collection of Microorganisms (CCM) having accession numbers CCM 4992, CCM 4993, CCM 4994, CCM 4995, CCM 4996, CCM 4997, or CCM 4998;
- and,
- (b) the at least one bacteriophage is a bacteriophage deposited with the Deutsche Sammlung von Mikroorganismen und Zellkulturen GmBH (DSM) having accession number DSM 14614, DSM 14615, or DSM 14616.
A bacteriophage, deposited with the DSM under accession number DSM 14614, DSM 14615, or DSM 14616.
Dependencies are inferred from the claim text.