Pre-operative device for localizing marked tissues and process using such a device

Device for pre-operative location of marked tissues, which comprises at least one probe (1) having an elongated shape and integrating at least two of three types of detection means selected from the group comprised by:

• at least one means (1) for the detection of radioactive radiation (3) emitted by tissues (4) marked with isotopes or radioactive colloids, generating a corresponding representative electrical signal (5);
• at least one optical detection means comprising at least one means (6) for emitting luminous radiation toward the tissues (4) and at least one means (7) for receiving and transmitting luminous radiation (8) reflected or emitted by fluorescence or luminescence by said tissues (4) marked by vital colorants toward at least one means for conversion (9) of said recovered luminous radiation (8) into a corresponding electrical signal (10);
• a means (15) for detecting magnetization or measuring magnetic susceptibility of the tissues (4) marked by superparamagnetic substances, generating a corresponding representative electrical signal (16);
• and in addition to said at least two types of detection means, means for transmitting or conveying said electrical signals (5, 10, 16) and at least one electronic means (11) for processing electrical signals (5, 10, 16) conveyed by the last-named means, so as to display, superimpose, inlay and/or edit a reconstituted image (12), at least partial, of the tissues (4) marked by said colorants and simultaneously supplying a physically perceptible expression (12′) of the representative electrical signal (5) delivered by the detection means (2) of the radioactive radiation (3) emitted by the radioactively marked tissues (4) and/or of the representative electrical signal (16) delivered by the means (15) for detecting the magnetization or measuring the magnetic susceptibility of the tissues (4) marked by superparamagnetic substances.